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Project manager Bioinformatics for large scale whole genome sequencing projects to advance genomic medicine

A BioIT/Bioanalyst position is available in the team of Prof. Joris Vermeesch (KU Leuven/UZ Leuven, Belgium) in association with the Genomics Core.

The laboratory of cytogenetics and genome research in the center for human genetics develops tools for genome analyses. This position will be embedded in the KU Leuven Genomics Core, the largest sequencing facility in Belgium. We offer a broad portfolio of NGS techniques which are made available for academic labs, companies and hospitals. As a partner in the European sequencing network, EASI genomics, we harmonize and benchmark novel sequencing technologies.


For more info, contact Prof. Joris Vermeesch (joris.vermeesch@kuleuven.be) or Dr. Wouter Bossuyt (wouter.bossuyt@uzleuven.be).You can apply for this job no later than July 18, 2022 via the online application toolKU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.




Health Care
Apply before: 18/07/2022

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You will be a project manager and bio-IT specialist to coordinate large scale whole genome sequencing projects. As such, you will lead the technology push and tackle the challenges of contemporary genome analysis such as implementing de novo assembly and haplotyping of human genomes combining both short (Illumina) and long read (PacBio and ONT) sequencing technologies. You will work with the genomic database developers, leverage national and international genomic data sharing and will work with both national (Elixir/VIB and IMEC) and international teams (1+MG) building a genomic medicine cluster.
You will:

  • lead development and implementation efforts to enable telomere-to-telomere genome assemblies
  • lead the large multi-centric sequencing efforts leveraging genomic medicine
  • lead and coordinate with other team members development of databases, analytical platforms and implementation of novel and existing analytical tools/pipelines
  • communicate results in professional manner in spoken and written English with consortium members and (international) users
  • manage the (bio) IT component of clinical trials
  • build solutions to leverage genomic medicine.

You ideally have:

  • a PhD in a relevant BioIT domain and experience with project management
  • strong computational, programming and/or data analysis skills with an IT, BioIT or engineering background
  • experience in analyzing high-throughput sequencing data, databasing and/or data analysis are assets
  • problem-solving attitude to work and critical analytical thinking
  • a keen interest and motivation to work on ambitious projects in a dynamic, driven team
  • knowledge of genetics (desirable, not a prerequisite)
  • the ability to meet timelines and work accurate

The group is involved in several large scale sequencing projects. We are applying whole genome short and long read sequencing to identify the causes of rare diseases and leveraging genomic medicine. The project involves leading the Bio IT aspects of prospective multicentric randomized trial to diagnose rare diseases in Belgium (BESolveRD, https://beshg.be/workgroups/besolverd); the long read sequencing efforts to map rare diseases; efforts aimed at sequencing over 10k individuals to build the Belgian Genome Biobank and participation in the European 1million genome project (1+MG).
We have onsite access to state-of-the-art facilities, including single cell analysis platforms, Flow cytometry, High-Throughput Sequencing (Illumina, PacBio and ONT), Bioinformatics, Imaging, high-capacity computing and others. You will be embedded within the KU Leuven Genomics Core facility (https://www.genomicscore.be/), the largest sequencing facility in Belgium, which offers a broad portfolio of NGS techniques for academic labs, companies, and hospitals. We are committed to inclusivity and diversity in the workplace, and value a positive, empowering and actively engaging attitude in every team member. Located in Leuven, a small but vibrant and international town by the river Dijle where centuries of history meet cutting-edge science, we are only a stone’s throw away from the cosmopolitan city of Brussels, the heart of Europe. We are part of the University of Leuven, one of the oldest and most prestigious universities of Europe. Founded in 1425, it is Belgium’s largest university, currently featuring among the best universities in the world according to the Times Higher Education and recently ranked as Europe’s most innovative for the third year in a row.
The earliest start date of the position is August 1st, 2022. We offer a 3-year position on a competitive salary, pending positive evaluation after 1 year.

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