PHD STUDENT IN PRECLINICAL RESEARCH ON SARCOMA TREATMENT

Laboratory of Experimental Oncology is a dynamic and enthusiastic team of researcher working in the field of sarcoma translational research. We use our exclusive platform of patient-derived xenograft (PDX) models of sarcoma to study the biology of the disease and to evaluate novel therapeutic options in vivo.

Website unit https://gbiomed.kuleuven.be/en...

Project

Sarcoma is a heterogenous group of rare mesenchymal tumours with more than 90 distinct subtypes described. The limited treatment options available for advanced sarcoma patients underline the need for reliable preclinical models to test new therapeutic approaches. Our group established a unique panel of PDX models (XenoSarc)in nude mice, currently constituting of more than 70 different models from various human sarcoma subtypes. These models are well-characterised, making it a suitable platform for preclinical therapeutic target validation and drug evaluation in vivo, which are done in collaboration with academic centres and industrial partners. Your role in this project will be to perform in vivo experiments, testing novel therapeutic options in mouse models of sarcoma and analysing ex-mouse human tumours using histopathological and molecular techniques. Furthermore, you will be involved in creating and characterising novel PDX models.

For moreinformation please contact Dr. Agnieszka Wozniak, mail: agnieszka.wozniak@kuleuven.be.

More informationon the Doctoral School – cancer program can be found here: Doctoral School - cancer program – Cancer (kuleuven.be)

You can apply for this job no later than July 15, 2022 via the online application tool

KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.

Language

English

Sector

Government

Apply before: 15/07/2022

Apply now

Profile

You should have:

a Master degree in biomedical sciences or other relevant field, with the interest in oncology;
hands-on experience in histopathological and/or molecular techniques;
laboratory animal training (FELASA or comparable certificate) or motivated to complete it soon after starting the position; experience in animal work would be an advantage;
interest and motivation to work independently on ambitious projects in an enthusiastic team of researchers;
the ability to perform your research to the highest standards and integrity, work accurately and meet timelines;
team spirit, enjoying working in a multi-cultural group of colleagues and external collaborators;
excellent communication skills in spoken and written English through presentations, scientific papers and discussion with team members and our collaborators.

Offer

We are offering full time employment in an intellectually challenging environment. We have onsite access to state-of-the-art facilities, including high-throughput sequencing, bioinformatics, imaging, high-capacity computing, single cell analysis platforms, flow cytometry and others. KU Leuven is highly inter- and multidisciplinary focused and strives for international excellence. In this regard, it actively works together with research partners in Belgium and abroad.

You will work in Leuven, a historic, dynamic, and lively city located in the heart of Belgium, within 20 minutes from Brussels, the capital of the European Union, and less than two hours from Paris, London, and Amsterdam.

Applicants must hold a Master degree (or comparable qualification) when commencing the post.The earliest start date of the position is September 1st, 2022, but we are very happy to cater this for the ideal candidate. We offer a 4-year contract on a competitive salary, pending positive evaluation by our doctoral school after 1 year.