19 December 2018

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For more information please contact Prof. dr. Jan Cools, tel.: +32 16 33 00 82, mail:

You can apply for this job no later than January 31, 2019 via the online application tool
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Apply before 31 January 2019

The Molecular Biology of Leukemia laboratory (Professor Jan Cools, VIB - KU Leuven) is looking for a motivated postdoctoral researcher for studies of transcriptional regulation in leukemia.

The laboratory of Professor Jan Cools is located on the Gasthuisberg campus of the KU Leuven (Faculty of Medicine, Center for Human Genetics) and has on-site mouse facilities, sequence facilities and access to leukemia samples.

It Is also one of the research groups of the Center of Cancer Biology (CCB) - one of the VIB research centers at KU Leuven. VIB-KULeuven is an exciting, interdisciplinary research institute with excellent facilities and strong research groups in genetics, oncology, neurobiology, immunology, virology, molecular biology and translational research.
Recent publications
Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.Vanden Bempt M, Demeyer S, et al. Cancer Cell. 2018.
HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development. de Bock CE, et al. Cancer Discov. 2018.

Website unit


The project will focus on 

(i) the study of transcriptional complexes by ChIP-seq and Mass Spec analysis
(ii) the effect on transcription by other mutations
(iii) the use of leukemia mouse models to verify the relevance of these findings.

  • PhD in biology, biochemistry, biotechnology or equivalent
  • Strong expertise in basic research technologies (Western blotting, PCR, cloning, cell culture, flow cytometry, etc.)
  • Good publication record and strong communication skills in English
  • Experience with transcription factors, ChIP-seq, RNA-seq, etc. is a plus
  • Experience with mouse cancer/leukemia models is a plus

This position is open to both junior and experienced scientists. We look for highly motivated candidates with an interest in leukemia research and with a track record in cell biology, transcription factor function and/or mouse models. We provide a stimulating and strong scientific environment in a cancer department.


The Center for Human Genetics (KU Leuven) and the Center for Cancer Biology (VIB) entail an interactive and stimulating work and training environment with a dynamic and diverse scientific community and access state-of-the-art core facilities to successfully perform multidisciplinary research.