For more information please contact Prof. dr. Kim De Keersmaecker, tel.: +32 16 37 31 67, mail: firstname.lastname@example.org
The laboratory for Disease Mechanisms in Cancer (Department of Oncology, KU Leuven) is looking for a motivated postdoctoral researcher. Our team has a long-standing interest in studying the biology of acute lymphoblastic leukemia (ALL), and in particular we focus on the role of mutations in ribosomal proteins and their association with other mutations in ALL. Accumulation of mutations in ALL does not occur randomly, and particular lesions show significant co-occurrence or mutually exclusivity in the leukemia cells. This project aims at studying the molecular biological mechanisms by which co-occurring oncogenic events in T-cell ALL cooperate with each other to drive leukemia development, and how this can result in new vulnerabilities of the leukemia cells to drug treatment.